Transactions on Case-Based Reasoning

Volume 3 - Number 1 - October 2010 - Pages 17-27

Adaptation Problems focusing on Endocrine Therapy Support

R. Schmidt and O. Vorobieva

Institute for Biostatistics and Informatics in Medicine and Aging Research, University of Rostock, D-18055 Rostock, Germany


So far, Case-Based Reasoning has not become as successful in medicine as in some other application domains. One, probably the main reason is the adaptation problem. In Case-Based Reasoning the adaptation task still is domain dependent und usually requires specific adaptation rules. Furthermore, in medicine adaptation is often more difficult than in other domains, because usually more and complex features have to be considered. We have developed some programs for endocrine therapy support, especially for hypothyroidism. In this paper, we do not present them in detail, but focus on adaptation. We do not only summarise experiences with adaptation in medicine, but we want to elaborate typical medical adaptation problems and hope to indicate possibilities how to solve them.

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